| First Name | Desmond |
| Last Name | Hume |
| Full Name at Birth | Desmond David Hume |
| Other Names | BrothaDes |
| Birthplace | Glasgow, Scotland, UK |
| Distinctive Features | calls everyone of "brother" |
| Nationality | Scottish |
Desmond David Hume is a fictional character on the ABC television series Lost portrayed by Henry Ian Cusick. Desmond's name is a tribute to David Hume, the famous empiricist author and philosopher. Desmond was not a passenger of Flight 815. He had been stranded on the island three years prior to the crash as the result of a shipwreck. Desmond eventually leaves the Island with the Oceanic 6 and is reunited with his love Penny Widmore (Sonya Walger).
The fictional character, Desmond Hume, has appeared in the following films and TV series: